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Latest news:

Sep 26, 2010:
DireX presentation and tutorial at EMBL Heidelberg on Oct 5 (2010).

Oct 25, 2009:
DireX will be presented at the NCMI Workshop for Cryo-EM Modeling in Houston, Jan 14-17 (2010)

Publications

23. Z. Wang, G.F. Schröder. Real-space Refinement with DireX: From Global Fitting to Side-chain Improvements. Biopolymers (2012), accepted.
22. R. Henderson, A. Sali, M.L. Baker, B. Carragher, B. Devkota, K.H. Downing, E.H. Egelman, Z. Feng, J. Frank, N. Grigorieff, W. Jiang, S.J. Ludtke, O. Medalia, P.A. Penczek, P.B. Rosenthal, M.G. Rossmann, M.F. Schmid, G.F. Schröder, A.C. Steven, D.L. Stokes, J.D. Westbrook, W. Wriggers, H. Yang, J. Young, H.M. Berman, W. Chiu, G.J. Kleywegt, C.L. Lawson. Outcome of the First Electron Microscopy Validation Task Force Meeting. Structure (2012), in press.
21. D.J. O'Donovan, I. Stokes-Rees, Y. Nam, S. Blacklow, G.F. Schröder, A.T. Brunger, Piotr Sliz. A grid-enabled web service for low-resolution crystal structure refinement. Acta Cryst. D (2011), accepted.
20. A.T. Brunger, D. Das, A.M. Deacon, J. Grant, T.C. Terwilliger, R.J. Read, P.D. Adams, M. Levitt and G.F. Schröder. Application of DEN-Refinement And Automated Model-Building To A Difficult Case Of Molecular Replacement Phasing: The Structure Of A Putative Succinyl-Diaminopimelate Desuccinylase From Corynebacterium Glutamicum. Acta Cryst. D (2011), accepted.
19. V.E. Galkin, A. Orlova, D. Kudryashov, A. Solodukhin, E. Reisler, G.F. Schröder, and E.H. Egelman. Remodeling of Actin Filaments by ADF/Cofilin Proteins. PNAS (2011), accepted.
18. S. Gao, A. von der Malsburg, A. Dick, K. Faelber, G.F. Schröder, O. Haller, G. Kochs, O. Daumke. Three domain architecture of dynamin-like MxA GTPase. Immunity (2011) 35:514-525. [PDF]
17. Y. Cong, G.F. Schröder, A.S. Meyer, J. Jakana, B. Ma, M.T. Dougherty, M.F. Schmid, S. Reissmann, M. Levitt, S.L. Ludtke, J. Frydman, and W. Chiu. Symmetry-Free Cryo-EM Structures of the Chaperonin TRiC Along its ATPase-Driven Conformational Cycle. EMBO J (2011), accepted.
16. E. Jaenicke, K. Büchler, H. Decker, J. Markl, T. Barends, and G.F. Schröder. The Refined Structure of Functional Unit h of Keyhole Limpet Hemocyanin (KLH1-h) Reveals Disulfide Bridges. IUBMB Life (2011) 63(3):183-187. [PDF]
15. L. Zerrad, A. Merli, G.F. Schröder, A. Varga, E. Gráczer, P. Pernot, A. Round, M. Vas, and M.W. Bowler. A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. JBC (2011) 286:14040-14048. [PDF]
14. T. Sabir, G.F. Schröder, A. Toulmin, P. McGlynn, and S.W. Magennis. Global Structure of Forked DNA in Solution Revealed by High-Resolution Single-Molecule Fluorescence Resonance Energy Transfer. JACS (2011) 133(5):1188-1191. [PDF]
13. V.E. Galkin, A. Orlova, G.F. Schröder, E.H. Egelman. Structural Polymorphism in F-actin. Nat Struct Mol Biol (2010) 17:1318-1323. [PDF]
12. G.F. Schröder, M. Levitt, A.T. Brunger. Super-resolution biomolecular crystallography with low-resolution data. Nature (2010) 464:1218-1222. [PDF]
See also "Preview" by Randy J. Read "From Poor Resolution to Rich Insight" Structure (2010) 18:664-665.
11. J. Zhang, M.L. Baker, G.F. Schröder, N.R. Douglas, S. Reissmann, J. Jakana, M. Dougherty, C.J. Fu, M. Levitt, S.J. Ludtke, J. Frydman, and W. Chiu. Mechanism of folding chamber closure in a group II chaperonin. Nature (2010) 463:379-383. [PDF]
10. A. K. Wozniak, G.F. Schröder, H. Grubmüller, C.A.M. Seidel, F. Oesterhelt. Single molecule FRET measures bends and kinks in DNA. PNAS (2008) 105(47):18337-18342. [PDF]
9. O.F. Lange, N.-A. Lakomek, C. Fares, G.F. Schröder, S. Becker, J. Meiler, H. Grubmüller, C. Griesinger, B.L. de Groot. Atomistic residual dipolar coupling ensemble of ubiquitin reveals molecular recognition dynamics up to the microsecond timescale. Science (2008) 320:1471-1475. [PDF]
8. G.F. Schröder, A.T. Brunger, and M. Levitt. Combining Efficient Conformational Sampling with a Deformable Elastic Network Model Facilitates Structure Refinement at Low Resolution. Structure (2007) 15:1630-1641. [PDF]
7. G. F. Schröder, U. Alexiev, and H. Grubmüller. Simulation of fluorescence anisotropy experiments Probing protein flexibility. Biophys. J. (2005) 89:3757-3770. [PDF]
6. A. Wozniak, S. Nottrott, E. Kühn-Hölsken, G. F. Schröder, H. Grubmüller, R. Lührmann, A. M. Seidel and F. Oesterhelt. Detecting protein-induced folding of the U4 snRNA kinkturn by single-molecule multiparameter FRET measurements. RNA (2005) 11:1545-1554. [PDF]
5. G.F. Schröder; Simulation of Fluorescence Spectroscopy Experiments , PhD Thesis, Universität Göttingen, 2004. [PDF]
4. M. Margittai, J. Widengren, E. Schweinberger, G.F. Schröder, S. Felekyan, E. Haustein, M. König, D. Fasshauer, H. Grubmüller, R. Jahn, and C. A. M. Seidel. Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of Syntaxin 1. PNAS (2003) 100(26):15516-15521. [PDF]
3. G.F. Schröder and H. Grubmüller. Maximum likelihood trajectories from single molecule fluorescence resonance energy transfer experiments. J. Chem. Phys. (2003) 119(18):9920-9924. [PDF]
2. G.F. Schröder and H. Grubmüller. FRETsg : Biomolecular structure model building from multiple FRET experiments. Comp. Phys. Comm. (2003) 158:150-157. [PDF]
1. G.F. Schröder Molekulardynamiksimulation der Flexibilität und Fluoreszenzanisotropie eines an ein Protein gebundenen Farbstoffs, Diploma Thesis, Universität Göttingen, 2001. [PDF]