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Latest news:

Jul 10, 2021:
Our new JBC review on amyloid fibril structure determination by cryo-EM is out! HERE

Jul 10, 2021:
New preprint on bioRxiv: We present fibril structures of alpha-synuclein amplified from the brain of Parkinson and MSA patients: HERE

May 7, 2021:
Congratulations Christine on your excellent PhD defense!!

Sep 25, 2020:
New paper on biosensor engineering is out in Nat Commun, see HERE

Jun 15, 2020:
IAPP fibril paper is out in NSMB: HERE

Feb 12, 2020:
New preprint on bioRxiv: Amyloid fibril structure of islet amyloid polypeptide by cryo-electron microscopy reveals similarities with amyloid beta

Aug 21, 2019:
New publication in Nature Communications on the PI3K-SH3 amyloid fibril structure by Cryo-EM. see here.

Aug 7, 2019:
New DireX Version 0.7.1. Added a turbo mode, which is much faster (but less accurate). Download here.

Sep 10, 2017:
New publication in Science on the Abeta(1-42) fibril structure. see here.

Sep 1, 2017:
We have new job openings for postdocs and PhD students, see here.

Jul 10, 2017:
Congratulations to Michaela, Amudha, and Tatjana on their successful PhD Defenses!

Dec 4, 2015:
Congratulations to Dennis on his successfull PhD Defense!

Nov 22, 2015:
New publications on our protein structure refinement method and CASP11 results.

Feb 3, 2015:
Congratulations to Zhe on his successfull PhD Defense!

Software


DireX
Conformational sampling under (low resolution) experimental restraints. Is used for flexible fitting of models into CryoEM density maps.


FRETsg
Structure building from multiple FRET distances.

FretTrace
Maximum likelihood trajectories from single-molecule FRET experiments.

g_lmla Implementation of the local-mean-by-linear-assignment algorithm to compute curvilinear principal coordinates.

coming soon:
g_spline
Spline interpolation between multiple structures

g_rdc
Compute residual dipolar couplings from MD trajectories